Many heterosexual men who've been in relationships with women will take the view that women are 'weird creatures' and that they can't live with them or without them.
In turn many heterosexual women who've had relationships with men will take the view that men too are 'weird creatures' and that they can't live with them or without them.
But it is also possible that someone who's been in relationships with men and women would take the view that both genders are weird.
In addition gay men may find men to be weird creatures and gay women women to be weird creatures.
It would seem that it all depends on who you have relationships with since it is through relationships, and the emotional interpersonal neurosis that usually comes with them, that you see people in all their weirdness, heterosexual people thereby assuming it has something to do with someone's sex rather than it being generally true of everyone.
My contention, you will have guessed, is that both men and women are weird creatures because humans are weird.